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Primary Immunodeficiency Diseases

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Primary immunodeficiency diseases are a group of more than 350 rare, chronic disorders in which part of the body’s immune system is missing or functions improperly. These diseases are caused by hereditary or genetic defects. Because one of the most important functions of the normal immune system is to protect against infection, people with primary immunodeficiency diseases commonly have an increased susceptibility to infection.


Immune Deficiency Foundation

Contact: 800-296-4433
Population Served:

Patients and families affected by primary immunodeficiency diseases


To improve the diagnosis, treatment and quality of life of persons with primary immunodeficiency diseases through advocacy, education and research.

  • Provides educational information and up-to-date publications
  • Connects patients and their families with others who have gone through similar situations to share experiences, encouragement and understanding
  • Patients receive individual help with questions about insurance, physician location, personalized instructional materials, and access to care and treatment
  • Local, regional and national level educational meetings featuring leading immunologists
  • Consulting Immunologist Program provides physicians the opportunity to consult with expert clinical immunologists about patient-specific questions and obtain valuable diagnostic, treatment and disease management information.