Search Results

Myeloproliferative Neoplasms

Myeloproliferative neoplasms (MPNs) are types of blood cancer that begin with an abnormal mutation (change) in a stem cell in the bone marrow. The change leads to an overproduction of any combination of white cells, red cells and platelets.

A phase 1 study of CB-010, a CRISPR-edited allogeneic CAR-T targeting CD19, in patients with B-cell NHL

In February 2021, LLS made an equity investment in Caribou Biosciences to support "A Phase 1, Multicenter, Open-Label Study of CB-010, a CRISPR-Edited Allogeneic Anti-CD19 CAR-T Cell Therapy in Patients With Relapsed/Refractory B Cell Non-Hodgkin Lymphoma." Caribou is a leading clinical-stage biotechnology company, co-founded by CRISPR pioneer and Nobel Prize winner Jennifer Doudna, Ph.D., using next-generation CRISPR genome-editing technology to develop “off-the-shelf” (allogeneic) CAR therapies for hard-to-treat blood cancers.

Marisa

Throughout my father’s journey, I was impressed by his care team, the advanced medicine used to treat blood cancer today, the individuals I met, people’s generosity, and the organizations I was introduced to. This journey opened my eyes to various organizations such as Be the Match and The Leukemia & Lymphoma Society (LLS). 

Linda

My blood cancer story began in 2015 with a diagnosis of chronic myeloid leukemia (CML). It was scary, and there were so many unknowns. Today it’s 9½ years later, and I know a few more things about blood cancers.

First, today my cancer is undetectable! But as my doctors have told me, it’s chronic, so I’ll always have to be proactive and take medication.

LLS Researchers

Partnering for Cures – Our Unique Collaborations Span Continents

Cathy

I had blood cancer and for that, I’m lucky. I’m not being facetious, I really believe I’m lucky. The doctors told me that Stage 2 Hodgkin lymphoma (HL) is highly treatable and this is the cancer to have if you’re going to get cancer. But that’s not the only reason why I’m lucky. The very first philanthropic effort that I did with my BFF was when we were 17 years old and allowed to donate blood. This is one of the first times I realized I was lucky. By giving blood I could give the gift of life. It’s something I also had in common with my husband who is an avid blood donor.

Jack

On October 19, 2018, after complaining about excruciating pain in his back, we took our 16-year-old son Jack to see the pediatrician. The doctor checked him out and told us to immediately get him to the Children's Hospital of Colorado and go to the 7th floor to see Dr. Maloney. Not paying attention and thinking nothing was wrong, we didn't notice that the 7th floor was the Center for Cancer and Blood Disorders. We met with doctors, had a blood test done, and they came back with the dreaded words, "Your child has cancer." Specifically, he had acute lymphoblastic leukemia (ALL).

Liz

In December 2010, my fiancé, Darla, was diagnosed with stage 4 small B-cell lymphoma (NHL). Her doctors developed a plan to start her on chemotherapy as soon as possible. She became very sick over the next couple of weeks. When she went to her first treatment three weeks after diagnosis, they could not administer the chemotherapy due to her being so ill. They put it off for a day and began Rituxan® treatment the next morning. She began having an allergic reaction to the drug. They stopped the treatment and tried to stabilize her, but later that evening, she passed away.

Angela

My name is Angela, and I have myeloproliferative neoplasms (MPN), a rare blood cancer. I was diagnosed when I was 16. I had a series of blood tests done after being raped, and that began my cancer journey. I began cancer treatment even though at that time (the late 90s) my condition was known as a “blood disorder” not cancer. In my early 20s, I suffered strokes, a heart attack, and a brain hemorrhage. I survived. I struggled to get and stay pregnant and was on life support after having my daughter prematurely at 26 weeks and six days. And I survived.

Lisa

I noticed some lymph nodes popped up on my neck so I went to the Dr. I didn't feel bad at all. My Dr ordered blood work and my white blood count was high. I was sent to The Cancer Center of Acadiana and more blood work, scans, ultrasound and bone biopsy was done. After all the results came in my white blood count was 99,000 and I had 75% leukemia cells in my bone marrow. I was diagnosed with CLL. 4 days later I was in the Infusion room at The Cancer Center of Acadiana. After 5 months of chemo going 2 days every month I am leukemia free.

Gabe

Just after I turned 12 years old, I was diagnosed with blood cancer. LLS supported me and my family as I endured chemotherapy treatment to be cancer free and beat Burkitts lymphoma. Now 16, I am inspired everyday to work hard in school to achieve my goal of becoming an oncologist to help kids, like me, beat blood cancer. Thank you LLS!

Rob

My blood cancer story started in 1987 when I was diagnosed and treated for testicular cancer with surgery and chemotherapy. As I progressed to the end of the chemo regimen, my blood counts would not return to normal. A bone marrow biopsy showed that I had developed treatment-related acute myeloid leukemia (AML) as a result of the chemotherapy for the testicular cancer.

Mendya

First, I must express appreciation to The Leukemia & Lymphoma Society (LLS) for providing educational resources, knowledge, and financial assistance to those of us affected by blood cancer. LLS spotlights blood cancer and gives a voice to so many like myself. Thank you. As a way to show my support to LLS and to raise awareness, I have raised $210 in September 2023, Blood Cancer Awareness Month (BCAM), via Facebook. This is just the beginning of my advocacy. 

Quade

Quade “Q” Marks is a 14-year-old freshman at East High School in Denver, Colorado.  He loves to play lacrosse, ski, snowboard and aspires to be a trauma surgeon. He is also a blood cancer survivor.

Sasha

When five-year-old Sasha had her birthday in June, there was more to celebrate this year — she had just gotten her port removed and was officially done with blood cancer treatment.

Sasha was just 2 years old when she was diagnosed with acute lymphoblastic leukemia in October 2017.  She began intense treatment right away, which continued until right before her fifth birthday. Sasha spent countless days at the hospital fighting for her life and enduring the brutal side effects that came with treatment, but she never lost her charming personality and bright smile.

Jesse

My name is Jesse Jordan. I'm a 37 year cancer survivor. I was diagnosed with acute lymphocytic leukemia (ALL) when I was 17 months old. Cancer has been one of the defining moments of my life and it helps me keep the right perspective towards life. The moment I take life for granted, cancer reminds me of how precious life is and how blessed I am to be here. I believe I am meant to share my cancer story with others. Cancer increases my awareness of life every day and reinforces my commitment to help others. My hope is that my personal cancer story can give hope to others.

Nikolas

Hello, my name is Nikolas Davison. I am 14 years old (almost 15 in July) and have battled acute lymphoblastic leukemia (ALL) for the past four years, but I am now done with chemo and getting my port removed soon.

In November 2016, I was misdiagnosed with appendicitis and was taken to the hospital by my father, where they took my blood and ran several tests. This was a painful experience to go through and I was very scared. After more tests, they knew that I had cancer. I was shocked, scared and horrified. I never thought in a million years that I would get cancer.

Blake

Blake was recently diagnosed with acute lymphoblastic leukemia (ALL), and is now in interim maintenance.

It all started with unexpected wrist and ​leg pain that turned into three years worth of treatments and procedures. We were told he was anemic so we took him in for iron supplements. He then got very constipated and had terrible side and tummy pains, which led us back into the ER. They gave us laxatives and sent us home.

Jim & Leslie

Jim and Leslie Donigan have been married for almost 50 years. Currently retired with three adult children, they have both faced a cancer diagnosis, but are in remission today.

In October of 2003, Leslie was diagnosed with a stomach cancer called GIST (Gastrointestinal Stromal Tumors) and was told it was terminal. But then her doctor tried a medication intended for blood cancer—and it worked.

Joy

On December 29, 2011, I heard those numbing words “you have cancer.” I was 23 years old, about to turn 24 and my whole world came to a screeching halt. After months of feeling “off,” multiple visits to all kinds of doctors, repeat blood work, scans and biopsies, it was finally determined that I had non-Hodgkin’s lymphoma.

Matt

Meet Matt. Hodgkin Lymphoma Survivor. Goalkeeper of major league soccer's Columbus Crew. After donating blood when he was 17 years old, Matt learned he had Stage 4 Hodgkin lymphoma. While all of his friends were going off to college, Matt was going to chemotherapy. But thankfully, by September, 2007 Matt was cancer free. Today, Matt is doing all he can to help others with blood cancer.

Anna

I was a recipient of The Leukemia & Lymphoma Society’s (LLS) Scholarship for Blood Cancer Survivors this year. I was diagnosed with acute myeloid leukemia (AML) on December 23, 2014. I received over 80 doses of chemotherapy, 40 blood product transfusions, and had six infections. One of these infections landed me in the pediatric intensive care unit for seven days with acute respiratory failure and sepsis. I spent 133 days in-patient at the hospital. In May 2015, I left the hospital for good and am celebrating seven years in remission.

Charlene

Cancer. That is a word that is scary. So many of us have friends, family and co-workers that are impacted by some type of cancer, but you never think it will be you. The word conjures up fear. Fear of treatment, fear of death and fear of what will be expected of you to deal with and hopefully survive. 

Suzanne

In January 2021, I received my diagnosis after five months of multiple doctor visits, blood work, and biopsies. I had no common symptoms such as night sweats or fatigue, just a small lump behind my ear. It was removed, and the pathology came back as non-cancerous. About six or so weeks later, another lump showed up. I decided to switch doctors, and they also didn't feel it was cancer based on my chart. But after they removed it, the pathology shared a much different story.

Gisenia

In October 2015, Gisenia Reyes heard the words "You have cancer." Diagnosed with acute myeloid leukemia (AML), an aggressive type of blood cancer. She immediately underwent chemotherapy treatment to save her life.

Gisenia attained remission status, however, she still had a mutation in her blood work, which could cause her to relapse.