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Signs and Symptoms

Children who have juvenile myelomonocytic leukemia (JMML) may have the following signs and symptoms:

  • Difficulty breathing and/or dry cough
  • Enlarged lymph nodes
  • Abdominal pain and loss of appetite caused by enlarged kidney, liver and/or spleen
  • Bone and joint pain
  • Fatigue and pale skin (from low level of red blood cells) 
  • Easy bruising and bleeding (from low level of platelets)
  • Frequent infections (from low level of white blood cells)

Some children also have skin changes which can include

  • Raised red bumps in the skin (maculopapular rash)
  • Bluish or greenish discolorations (chloromas)
  • Smooth coffee-colored skin lesions 

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