Therapy for chronic lymphocytic leukemia (CLL) sometimes produces side effects. Side effects from kinase inhibitor drugs and monoclonal antibody therapy are generally milder than side effects from chemotherapy.
For most patients, treatment side effects are temporary and go away once therapy ends. For other patients, side effects can be more severe, sometimes requiring hospitalization. Some patients never have side effects.
Before you undergo treatment, talk with your doctor about potential side effects. Drugs and other therapies can prevent or manage many side effects.
Common Side Effects
Chemotherapy drugs are the main culprits when it comes to causing unwanted side effects. These drugs can kill cancer cells, but they but damage normal cells, too. The lining of the mouth, throat, stomach and intestines are particularly vulnerable to damage. What's more, CLL produces symptoms that can be made worse by treatment.
The following side effects are common to chemotherapy and, to a lesser extent, monoclonal antibody therapy and other drug therapies. Click here to read more about these side effects.
- Extreme fatigue
- Hair loss
- Nausea and vomiting
- Mouth sores
- Aches and pains
- Low blood pressure
- Low levels of red cells, white cells and platelets in the blood
- Anemia (caused by a low red cell count)
Click here to read about specific drugs.
Long-Term and Late Effects
For some patients, side effects may last well after they finish treatment. To read more about lingering side effects, see The Leukemia & Lymphoma Society’s free publication, Long-Term and Late Effects of Treatment for Adults.