X4 Pharmaceuticals’ Presentations at ASH 2022 Further Highlight Opportunity for Mavorixafor in the Treatment of Chronic Neutropenia
Current TAP Partner
BOSTON, Dec. 12, 2022 - X4 Pharmaceuticals (Nasdaq: XFOR), a leader in the discovery and development of novel small-molecule therapeutics to benefit people with diseases of the immune system, today provided a summary of its chronic neutropenia-related presentations at this year’s annual meeting of the American Society of Hematology (ASH), taking place December 10-13, 2022 in New Orleans.
In an oral presentation entitled “Mavorixafor for Patients With Chronic Neutropenic Disorders: Results From a Phase 1b, Open-Label, Multicenter Study,” Julia T. Warren, M.D., Ph.D., Hematologist at Children’s Hospital of Philadelphia and Assistant Professor of Pediatrics at the Perlman School of Medicine at the University of Pennsylvania, presented positive data from a Phase 1b clinical trial evaluating the ability of X4’s lead clinical candidate, mavorixafor, to increase absolute neutrophil count (ANC) in people with idiopathic, cyclic, or congenital chronic neutropenia as monotherapy or concurrently with injectable granulocyte colony-stimulating factor (G-CSF).
Poster #2407, entitled “Prevalence of Chronic Neutropenic Disorders in the United States: A Retrospective Analysis of a Large Claims Database,” estimated that in 2021, between 37,000–48,000 people in the United States were living with a diagnosis of idiopathic, cyclic, or congenital neutropenia.
Poster #3575, entitled “Patient and Health Care Professional Perspectives on Quality of Life and Unmet Needs of People With Chronic Neutropenia: A Survey-Based Assessment,” highlighted responses of 100 patients/caregivers and 10 healthcare professionals (HCPs) to a survey on the experiences of people living with chronic neutropenia.