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Translational Research Program (TRP) guidelines

The goal of translational research is to reduce the time between laboratory findings and actual treatment.


The Translational Research Program (TRP) puts you on the bench-to-bedside fast track when it comes to finding better treatment and cures for leukemia, lymphoma and myeloma. The Leukemia & Lymphoma Society funds new and innovative research that shows high promise for translating basic biomedical knowledge to clinical application. 


Limited to a maximum of $200,000.00 annually, which includes direct costs and a maximum overhead of $19,982.00 or 11.1 percent of direct costs per year for three years. Budget requests must be carefully justified and commensurate with the project's needs.


Application Renewal

Grants are eligible for an additional two years if they include an approved clinical trial and a fully justified research plan. One of the program's principal intents is to permit the acquisition of sufficient data to apply to an appropriate agency or sponsor for sustained support.


2021-2022 Application Timeline



Call For Proposals August 30, 2021
Letter of Intent Due October 29, 2021, 3:00 PM ET
Full Application Due January 21, 2022, 3:00 PM ET
Panel Review Meetings March 2022
Award Notification* May 2022
Award Start Date July 1, 2022

*LLS’s non-negotiable Grant Agreement Terms & Conditions are available on

Any application components whose deadlines fall on a weekend or US holiday will be accepted before 3:00 PM (ET) on the US business day immediately following the above-listed date.


How to Apply

The Translational Research Program (TRP) application will be completed in 2 phases: Letter of Intent and Full Application. Below are step-by-step instructions for applying:

  • ​​Follow the instructions on the LLS Research Portal and in the Guidelines & Instructions to complete and submit your Letter of Intent (LOI). You will receive an email notifying you of your LOI approval status.

  •  Submit your Full Application to LLS for review prior to the Full Application deadline. We strongly recommend submitting at least 1 week in advance of the deadline, as site traffic on the day of and days leading up to the deadline will be heavy. No exceptions will be made for any reason for late applications

At any time during the application process, including after submitting your Full Application, you can check the status of your application by logging in to the LLS Research Portal, selecting your application (in either “New or Pending” or “Submitted” under Requests) and referring to the Status in the yellow box at the top of the page.

If you have any technical difficulties with the LLS Research Portal powered by Fluxx, please contact us via email at


Frequently Asked Questions

Where can I find the Policies and Procedures?

The Policies and Procedures are available to download from the TRP webpage or from the LLS Research Portal program information pages.

Are corporate entities allowed to apply?

No. Only academic institutions are eligible to receive funds from LLS Research Grants. Applicants from the National Institutes of Health or other government agencies are also not eligible. Corporations conducting blood cancer research may, however, be eligible to apply for Therapy Acceleration Program (TAP) funding.

How is independence defined?

Independence is defined as an academic appointment or similar non-corporate position that has sole responsibility for directing research and funding the work. Usually this means a professor, associate or assistant professor or an equivalent appointment. Post-doctoral and similar appointments are not considered independent positions.

May I submit more than one application?

No. Applicants may only serve as the PI for one new TRP application per cycle. Applicants are permitted to submit a new TRP and a Renewal TRP in the same cycle.

If I have an existing TRP award, can I apply for a second?

Yes, an investigator may apply for a new TRP if they currently hold an active TRP from a prior year. The proposed work may be a new research objective or may be related to the active TRP but should not directly overlap with the aims of the existing TRP.

Can I apply as a PI on one application and a Co-PI on another application?

No. Applicants may not serve as PI or Co-PI on more than one application within the same cycle. Applicants may, however, serve as Co-Investigator on more than one application.

Should Co-Investigators and Co-PIs conduct their research at the same institution as the PI?

Not necessarily. A Co-PI or Co-Investigator may work at a different institution – or even in a different country – from the PI.

Should my proposal be responsive to the request for proposals (RFP) topics?

Not necessarily. The LLS seeks proposals that are responsive to the RFP but will consider other exceptional proposals with the near-term potential of clinical translation.

What are permissible costs?

Permissible Direct Costs include salary, wage, or stipend with fringe benefits, supplies & materials, equipment, travel, and patient care costs. Permissible Indirect Costs include those incurred for common or joint objectives that cannot be readily identified with a particular project (general maintenance, utilities, library, etc.), as defined in Office of Management and Budget Circular A-21. Impermissible Costs include membership dues, tuition, books, journals, and publication costs.

Are subcontracts allowed?

Yes. The signing institution (i.e. the Sponsoring Institution) is responsible for academic and CRO subcontracts. LLS will only sign a contract with and dispense payments to the Sponsoring Institution and does not facilitate subcontracts.

Could this grant cover any subcontract costs?

Yes. While LLS does not facilitate subcontracts, subcontract costs may be claimed as part of the Sponsoring Institution’s direct costs. Indirect costs may only be claimed by one institution (usually the Sponsoring Institution).

Why is my administrative officer’s name missing from the online application dropdown menu?

In order for personnel to be selected from dropdown menus on the application, each individual must have an account in the LLS Research Portal (FLUXX) that is linked to the Sponsoring Institution of the application. Please contact to request new accounts.

Why can't I delete a document I upload?

In order to avoid accidental deletions, applicants are not granted access to delete uploaded documents. We recommend that all application documents be thoroughly reviewed before they are uploaded. Applicants wishing to correct an uploaded document should contact to have the document replaced with a corrected version. Please note that the correction will be apparent to reviewers.

Can I adjust the margins and font on the Project Description template?

No. Applications that are submitted with altered templates will be triaged.

Do character limits include spaces?

Yes. Character limits include spaces throughout all LLS grant applications.

What if my Human Subjects and Laboratory Animal assurances haven’t been approved before the application deadline (IRB, IACUC)?

Assurances pending approval should be noted on your application, and approval letters should be uploaded as soon as they are received. Approval letters received after the deadline should be sent to as soon as they are received and will be added to your application by LLS administrative staff.

Could someone switch labs before the grant start date of July 1st of the year in which the grant is awarded?

Yes. Applicants should alert LLS Research Administration of a potential move as soon as possible. The new Sponsoring Institution will be subject to LLS approval.

Need More Information?


Senior Director of Research Administration
The Leukemia & Lymphoma Society
3 International Drive, Suite 200
Rye Brook, NY 10573