BioInvent to hold two poster presentations at SITC 38th Annual Meeting
Lund, Sweden – September 27, 2023 – BioInvent International AB (“BioInvent”) (Nasdaq Stockholm: BINV), a biotech company focused on the discovery and development of novel and first-in-class immune-modulatory antibodies for cancer immunotherapy, today announces it will hold two poster presentations on its anti-tumor necrosis factor receptor 2 (TNFR2) programs at the Society of Immunotherapy for Cancer (SITC) 38th Annual Meeting, held November 3-5, 2023, in San Diego, California. The posters will showcase the latest data from a clinical Phase 1 trial evaluating the first-in-class antibody BI-1808 as single agent, as well as preclinical data for BI-1910. BI-1910 has received an IND approval and is expected to enter clinical development H2 2023.
Titles and numbers of the poster presentations are as follows:
- Title: Phase 1/2a Clinical Trial of BI-1808, a Monoclonal Antibody to Tumor Necrosis Factor Receptor 2 (TNFR2) as Single Agent and in Combination with Pembrolizumab.
Number: 757 - Title: Preclinical development of an agonistic anti-TNFR2 antibody (BI-1910) for cancer immunotherapy.
Number: 1368
The two anti-TNFR2 antibodies BI-1808 and BI-1910 are part of BioInvent’s tumor-associated regulatory T cells (Treg)-targeting program. TNFR2 is particularly upregulated on Tregs of the tumor microenvironment and has been shown to be important for tumor growth and survival, representing a new and promising target for cancer immunotherapy. In June 2023, the company announced strong interim safety data from the ongoing Phase 1/2a trial of BI-1808.
For further information about the conference, please refer to Home - SITC 2023 (sitcancer.org).