- Generic Name:
- Drug Type:
- BTK inhibitor
- How the Drug is Given:
Indications and Usage
Zanubrutinib is indicated for the treatment of adult patients with:
- Mantle cell lymphoma (MCL) who have received at least one prior therapy.
This indication is approved under accelerated approval based on overall response rate. Continued approval for this indication may be contingent upon verification and description of clinical benefit in a confirmatory trial.
- Waldenström’s macroglobulinemia (WM)
- Relapsed or refractory marginal zone lymphoma (MZL) who have received at least one anti-CD20-based regimen.
Side effects needing medical attention
The most common adverse reactions included neutrophil count decreased, platelet count decreased, upper respiratory tract infection, white blood cell count decreased, hemoglobin decreased, rash, bruising, diarrhea and cough.