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Details of the Drug
Generic Name:
Drug Type:
DNA-repair enzyme inhibitor
How the Drug is Given:

Intravenously (IV)


Indications and Usage

Topotecan is an FDA-approved cancer drug that is used to treat people who have certain types of cancer including acute myeloid leukemia and acute lymphoblastic leukemia. This drug may cause a temporary loss of hair in some people. After treatment with topotecan has ended, normal hair growth should return.

Side effects needing medical attention

Black, tarry stools; blood in urine or stools; cough or hoarseness (accompanied by fever or chills); fever or chills; lower back or side pain (accompanied by fever or chills); painful or difficult urination (accompanied by fever or chills); pinhead-sized red spots on skin or rash, hives and/or itching; shortness of breath, troubled breathing or fast or irregular breathing; unusual bleeding or bruising; large, hive-like swellings on the face, eyelids, mouth, lips and/or tongue; puffiness or swelling of the eyelids or around the eyes; tightness in chest or wheezing; unusual tiredness or weakness; changes in the skin color of the face.

For information on how to manage the costs of drug therapy, please see Financial Support, or to speak with an Information Specialist, call (800) 955-4572.