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Tazemetostat

Details of the Drug
Generic Name:
Tazemetostat
Drug Type:
Methyltransferase inhibitor
How the Drug is Given:
By mouth
Names:
TazverikTM
Tazemetostat

Indications and Usage

Tazemetostat is a methyltransferase inhibitor indicated for the treatment of:

  • Adult patients with relapsed or refractory follicular lymphoma whose tumors are positive for an EZH2 mutation as detected by an FDA-approved test and who have received at least 2 prior systemic therapies.
  • Adult patients with relapsed or refractory follicular lymphoma who have no satisfactory alternative treatment options.

These indications are approved under accelerated approval based on overall response rate and duration of response. Continued approval for these indications may be contingent upon verification and description of clinical benefit in a confirmatory trial(s).

Side effects needing medical attention

The most common adverse reactions in patients with follicular lymphoma are fatigue, upper respiratory tract infection, musculoskeletal pain, nausea, and abdominal pain.

For information on how to manage the costs of drug therapy, please see Financial Support, or to speak with an Information Specialist, call (800) 955-4572.