Mitoxantrone

Details of the Drug

Generic Name:: Mitoxantrone
Pronunciation:: my-toh-ZAN-trone
Drug Type:: Antitumor antibiotic
How the Drug is Given:: Intravenously (IV)
Names:: Novantrone®; Mitoxantrone

Indications and Usage

Mitoxantrone is FDA approved in combination with other approved drug(s) indicated in the initial therapy of acute nonlymphocytic leukemia (ANLL) in adults. Mitoxantrone is a dark blue solution that may cause urine to appear blue-green. It may also cause the whites of the eyes to turn a blue color. These effects are normal and last for only 1 or 2 days after each dose is given. This medicine often causes a temporary loss of hair. After treatment with mitoxantrone has ended, normal hair growth should return.

Side effects needing medical attention

If mitoxantrone accidentally seeps out of the vein, it may severely damage some tissues and cause scarring. Your healthcare provider should be notified right away if you notice redness, pain or swelling at the IV site; fast or irregular heartbeat; rash or itching; fever or sore throat; unusual bleeding or bruising; mouth sores.

For information on how to manage the costs of drug therapy, please see Financial Support, or to speak with an Information Specialist, call (800) 955-4572.