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Melphalan hydrochloride

Details of the Drug
Generic Name:
Melphalan hydrochloride
MEL-fa-lan HIGH-droe-KLOR-ide
Drug Type:
Alkylating agent
How the Drug is Given:

Intravenously (IV)

Evomela TM
Melphalan hydrochloride

Indications and Usage

U.S. Food and Drug Administration (FDA) has granted approval of EVOMELA for use in two indications:

  1. Use as a high-dose conditioning treatment prior to hematopoietic progenitor (stem) cell transplantation (ASCT) in patients with multiple myeloma (MM)
  2. For the palliative treatment of patients with MM for whom oral therapy is not appropriate.

This is the first product to be FDA-approved for the high-dose conditioning indication in MM.

Side effects needing medical attention

Low neutrophil count, low white blood cell count, low lymphocyte count, low platelet count, diarrhea, nausea, fatigue, low potassium in the blood, anemia, and vomiting.

For information on how to manage the costs of drug therapy, please see Financial Support, or to speak with an Information Specialist, call (800) 955-4572.