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Details of the Drug
Generic Name:
Drug Type:
DNA-damaging agent
How the Drug is Given:

By mouth


Indications and Usage

Chlorambucil is FDA approved to treat people who have chronic lymphocytic leukemia (CLL), some types of non-Hodgkin lymphoma and advanced Hodgkin lymphoma.

Side effects needing medical attention

Convulsions; cough; fever; chills; sore throat; flank or stomach pain; shortness of breath; rash; sores in the mouth and on the lips; swelling of feet or lower legs; unusual bleeding or bruising; yellowing of eyes and skin; black, tarry stools; blood in urine or stool; hoarseness; lower back or side pain; painful or difficult urination; pinhead-sized red spots on skin; agitation; blisters; hallucinations (seeing, hearing or feeling things that are not there); muscle twitching; peeling or scaling of skin; tremors; trouble walking; weakness (severe) or paralysis; changes in menstrual periods; itching of skin; nausea and vomiting.

For information on how to manage the costs of drug therapy, please see Financial Support, or to speak with an Information Specialist, call (800) 955-4572.