Asciminib
Details of the Drug
- Generic Name:
- Asciminib
- Drug Type:
- Kinase inhibitor (STAMP [Specifically Targeting the ABL Myristoyl Pocket] inhibitor)
- How the Drug is Given:
By mouth
- Names:
- Scemblix®
- Asciminib
Indications and Usage
Asciminib is indicated for the treatment of adult patients with:
- Newly diagnosed Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML) in chronic phase (CP).
This indication is approved under accelerated approval based on major molecular response rate. Continued approval for this indication may be contingent upon verification of clinical benefit in a confirmatory trial(s). - Previously treated Ph+ CML in CP.
- Ph+ CML in CP with the T315I mutation.
Side effects needing medical attention
Most common adverse reactions are upper respiratory tract infections, musculoskeletal pain, fatigue, nausea, rash, and diarrhea.
For information on how to manage the costs of drug therapy, please see Financial Support, or to speak with an Information Specialist, call (800) 955-4572.