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Jolanta Grembecka, PhD

Ann Arbor, MI
United States

Regents of the University of Michigan

Jolanta Grembecka, PhD, is an Associate Professor in the Department of Pathology at the University of Michigan. Her research has been focused on development of small molecule inhibitors of proteins involved in leukemogenesis. Her laboratory has developed the first small molecule inhibitors of the menin-MLL1 interaction as a treatment for acute leukemia. These efforts resulted in very potent compounds that advanced to clinical studies in acute myeloid leukemia patients. Her laboratory is also developing new targeted therapies for hematologic cancers by blocking novel epigenetic targets, including ASH1L histone methyltransferase as a treatment for acute leukemia. She received her PhD in Chemistry at Wroclaw University of Technology, Poland. She completed postdoctoral training at the University of Virginia, before starting her independent position at the University of Michigan. Dr. Grembecka is a co-author on over 80 peer-reviewed scientific publications and an inventor on 15 patents. She is a Leukemia and Lymphoma Society Scholar and American Cancer Society Research Scholar recipient.

Program Name(s)
Translational Research Program
Jolanta Grembecka