I am honored and grateful to receive the Scholar Award from The Leukemia & Lymphoma Society. This award will allow us to further investigate how metabolic pathways are used to enable epigenetic reprogramming in leukemia stem cells. These two mechanisms are dysregulated in a wide range of cancers including leukemia, and our recent studies have revealed that targeting metabolism and epigenetic regulators act synergistically to suppress leukemia. Our future studies may lead to novel strategies to treat leukemia by targeting these two mechanisms.