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LLS IMPACT guidelines

Making an Impact on Clinical Trial Access

The IMPACT Program is Now Open!

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LLS seeks to bring clinical trials to the patients through the Influential Medicine Providing Access to Clinical Trials (IMPACT) program. The overall goal is to expand access to high-quality clinical trials to patients by having clinical trial participation occurring at local community oncology centers. These clinical trials will be hosted by major cancer centers who will partner with community-based oncologists to facilitate recruitment and participation of patients at community oncology centers. Though all patients at these community centers are welcome in IMPACT, this program provides the opportunity to increase the participation of patients who are traditionally unrepresented in clinical trials, including those who are rural, minority, and/or economically disadvantaged.

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General Application Instructions

The IMPACT application will be completed in two phases. Letter of Intent and Full Application.

Mission Score

During the review process, each application shall receive two Mission Scores (in addition to the Priority Scores), which reflect the purpose of the program within LLS’s overall Mission. 

Community center participation:

  • Mission Score 1: High likelihood of increasing participation of patients at community centers in clinical trials above 20% within the grant timeframe.
  • Mission Score 2: Moderate likelihood of increasing participation of patients at community centers in clinical trials above 20% within the grant timeframe.
  • Mission Score 3: Low likelihood of increasing participation of patients at community centers in clinical trials above 20% within the grant timeframe.

Underserved community participation:

  • Mission Score a: High likelihood of increasing the participation of underserved communities in the community center-associated clinical trials.
  • Mission Score b: Moderate likelihood of increasing the participation of underserved communities in the community center-associated clinical trials. 
  • Mission Score c: Low likelihood of increasing the participation of underserved communities in the community center-associated clinical trials. 

Missions Scores of 1, 2, a, and b are fundable. Mission Scores of 3 and c are not fundable.