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Denileukin diftitox

Details of the Drug
Generic Name:
Denileukin diftitox
DEN-i-loo-kin DIF-ti-toks
Drug Type:
DNA-damaging agent
How the Drug is Given:

Intravenously (IV)

Denileukin diftitox

Indications and Usage

Denileukin diftitox is FDA approved to treat people who have persistent or recurrent cutaneous T-cell lymphoma whose malignant cells express the CD25 component of the IL-2 receptor.

Side effects needing medical attention

Back pain or lower back pain or side pain accompanied by fever or chills; chest pain; dizziness or faintness; difficulty swallowing; fast or irregular heartbeat; fever or chills; infection; rash; shortness of breath; swelling of face, feet or lower legs; warmth and flushing of skin; severe abdominal pain; black, tarry stools; cloudy urine; blood in urine or stool; cough or hoarseness accompanied by fever or chills; severe headache; loss of coordination; painful or difficult urination accompanied by fever or chills; pain in groin or leg; pinhead-sized red spots on skin; slurring of speech; sudden vision changes; swelling or pain at injection site; unusual bleeding or bruising; weakness of arms or legs; difficulty swallowing; loss of strength or energy; nausea; pain in joints and muscles; unusual tiredness or weakness; vomiting; cough; diarrhea; sore throat; trouble sleeping. 

For information on how to manage the costs of drug therapy, please see Financial Support, or to speak with an Information Specialist, call (800) 955-4572.