Amin Sobh, PhD
University of Florida
I am a postdoctoral research trainee at the University of Florida Health Cancer Center (UFHCC). I received a Ph.D. in Comparative Biochemistry from the University of California, Berkeley. My graduate research focused on the use of gene editing functional screens to study a variety of cellular processes including nutrient uptake and response to toxic substances. For my postdoctoral training, I decided to study hematologic malignancies. I joined the Laboratory of Dr. Jonathan Licht at UFHCC where I started to investigate the molecular and epigenetic mechanisms underlying pathogenesis of Multiple Myeloma (MM), a cancer of plasma cells that remains incurable. My current research focuses on identification of vulnerabilities associated with recurrent genetic lesions in MM. As most MM patients ultimately relapse by developing resistance to existing therapies, the ultimate goal of my work is to identify novel therapeutic targets to reverse drug tolerance and improve therapeutic outcomes.