Myeloproliferative Neoplasms

Myeloproliferative neoplasms are a type of blood cancer that includes myelofibrosis, polycythemia vera and essential thrombocythemia.

Myeloproliferative neoplasms (MPNs) are types of blood cancer that begin with an abnormal mutation (change) in a stem cell in the bone marrow. The change leads to an overproduction of any combination of white cells, red cells and platelets.

Types of MPNs

Essential Thrombocythemia

Essential thrombocythemia (ET) Is one of a related group of blood cancers known as “myeloproliferative neoplasms” (MPNs) in which cells in the bone marrow that produce the blood cells develop and function abnormally. Occasionally occurs in older children, but is mostly diagnosed in adult men and women.    What You Should Know Hematologists and oncologists are specialists who treat ...

Myelofibrosis

Myelofibrosis (MF) Is a rare bone marrow cancer. It is one of a related group of blood cancers known as “myeloproliferative neoplasms (MPNs)” in which bone marrow cells that produce the blood cells develop and function abnormally. The resulting fibrous scar tissue formation leads to severe anemia, weakness, fatigue and an enlarged spleen and liver. Is a type of chronic leukemia and can occur on its own (p...

Polycythemia Vera

Polycythemia vera (PV)     Is one of a related group of blood cancers known as “myeloproliferative neoplasms” (MPNs) in which cells in the bone marrow that produce the blood cells develop and function abnormally. Begins with one or more acquired changes (mutations) to the DNA of a single blood-forming cell. This results in the overproduction of blood cells. For all races and ethni...