Free Publications

Search for cll returned 189 results

Glossary Results

Relapsed CLL

CLL that responded to treatment but then returns.

Refractory CLL

CLL that has not responded to initial treatment. Refractory disease may be disease that is getting worse or staying the same (stable disease).

CD38

An antigen on CLL cells and other cells. The expression of CD38 may be a marker to assist in predicting CLL progression.

Richter transformation

In a small number of patients, there is a progression in their disease. In these patients, CLL takes on the characteristics of an aggressive lymphoma. This change is not a second cancer, but a transformation of the CLL cells.

Small lymphocytic lymphoma (SLL)

A disease with symptoms and treatment that are much like CLL. SLL starts in a lymphocyte in a lymph node. CLL starts in a lymphocyte in the marrow.

Immunoglobulin Heavy Chain Variable Region (IgHv) Gene Status

A marker that can distinguish between CLL subtypes (unmutated IgHv and mutated IgHv). People with CLL with unmutated IgHv gene status may have a more progressive form of the disease.

Zap-70

An abbreviation for the cell protein “zeta-associated protein 70.” A high level of ZAP-70 expression on the cells of patients with B-cell CLL is one of several factors that may predict more progressive disease. Outside of a research laboratory this test is generally not very reliable and should not be used.

Side Effects

Therapy for chronic lymphocytic leukemia (CLL) sometimes produces side effects. Side effects from kinase inhibitor drugs and monoclonal antibody therapy are generally milder than side effects from chemotherapy. For most patients, treatment side effects are temporary and go away once therapy ends. For other patients, side effects can be more severe, sometimes requiring hospitalization. Some patients never have side effects. Before you undergo treatment, talk with your doctor about ...

  • Photo
Read more

Chemotherapy and Drug Therapy

Chemotherapy Chemotherapy drugs are designed to kill cancer cells. They work by attacking cells that divide quickly. Chemotherapy is typically given in cycles, with each period of treatment followed by a rest period.  Standard chemotherapy drugs that doctors use to treat CLL as a single agent or in combination include: Antimetabolites Cladribine (Leustatin®) Fludarabine (Fludara®) Pentostatin (Nipent®) Alkylating agents Bendamustine hydrochloride (Bende ...

  • Photo
Read more

Traitement des LNH et de la LLC: comment décider?

Les spécialistes en information de la Société Leucémies et Lymphômes sont des diplômés de niveau 'masters' qui vous apporteront informations, ressources et soutien après votre diagnostic et au cours de votre traitement. Contactez un spécialiste en information Par téléphone au (800) 955-4572 Par courriel Sur Internet (Si un spécialiste bilingue est disponible, nous acceptons AnswerChat en français.) Veuillez visionner le nouveau programme vidéo: &nbs ...

Read more

Linfoma no-Hodgkin y leucemia linfocítica crónica: decisiones de tratamiento

Los especialistas en información de la Sociedad Leucemia & Linfoma (trabajadores sociales, infermeros y educadores de salud con nivel de maestría)  proporcionan información actualizada sobre los cánceres de la sangre, los tratamientos y los servicios de apoyo. Contacte un especialista en información Por telefono (800) 955-4572 Por correo electrónico Por Internet (Tomamos AnswerChat en español si un especialista bilingüe está disponible.) Le animamos ...

Read more

What To Do When Standard Therapy Fails: 2017 Clinical Trials Symposium

This symposium, chaired by Dr. Jane Winter of Northwestern’s Feinberg School of Medicine, is the second of its kind led by The Leukemia & Lymphoma Society. The half-day program will include 5 disease-specific sessions and 3 panel discussions all with the goal of educating referring physicians on the importance of recommending clinical trials to patients when standard therapy is no longer an option, with attendees learning about the clinical trials currently being held at Chicago’s l ...

Read more

Pages

Glossary Results

Relapsed CLL

CLL that responded to treatment but then returns.

Refractory CLL

CLL that has not responded to initial treatment. Refractory disease may be disease that is getting worse or staying the same (stable disease).

CD38

An antigen on CLL cells and other cells. The expression of CD38 may be a marker to assist in predicting CLL progression.

Richter transformation

In a small number of patients, there is a progression in their disease. In these patients, CLL takes on the characteristics of an aggressive lymphoma. This change is not a second cancer, but a transformation of the CLL cells.

Small lymphocytic lymphoma (SLL)

A disease with symptoms and treatment that are much like CLL. SLL starts in a lymphocyte in a lymph node. CLL starts in a lymphocyte in the marrow.

Immunoglobulin Heavy Chain Variable Region (IgHv) Gene Status

A marker that can distinguish between CLL subtypes (unmutated IgHv and mutated IgHv). People with CLL with unmutated IgHv gene status may have a more progressive form of the disease.

Zap-70

An abbreviation for the cell protein “zeta-associated protein 70.” A high level of ZAP-70 expression on the cells of patients with B-cell CLL is one of several factors that may predict more progressive disease. Outside of a research laboratory this test is generally not very reliable and should not be used.