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Clinical trials

Careful studies done by doctors to test new drugs or treatments, or new uses for approved drugs or treatments. The goal of clinical trials for blood cancers is to improve treatment and quality of life and to find cures.

Epigenetic Change

Any change that alters gene activity without changing the DNA sequence. Many types of epigenetic changes have been identified. While epigenetic changes are natural and essential to many of the body's functions, certain epigenetic changes can cause major adverse health effects, including cancer. Drugs that target specific epigenetic changes - for example, the histone deacetylase (HDAC) inhibitor vorinostat (Zolinza® )- are approved to treat some blood cancers and are being studied in clinical trials for treatment of other blood cancers

UCLA Health Joins The Leukemia & Lymphoma Society’s Innovative Clinical Trial

UCLA Health is the latest major cancer research institution – and the first in Southern California – to join LLS’s Beat AML Master Clinical Trial

The Beat AML Master Clinical Trial is a paradigm-shifting collaboration to bring precision medicine to patients with acute myeloid leukemia and is the first precision-medicine clinical trial for a blood cancer, in which multiple therapies are being tested simultaneously against multiple subtypes of acute myeloid leukemia, one of the ...

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LLS ANNOUNCES COLLABORATION WITH THE NATIONAL CANCER INSTITUTE AND CHILDREN’S ONCOLOGY GROUP ON A GLOBAL MASTER CLINICAL TRIAL FOR CHILDREN WITH ACUTE LEUKEMIA

The Leukemia & Lymphoma Society (LLS) announced today a collaboration with the National Cancer Institute (NCI) and the Children’s Oncology Group (COG) to launch a global precision medicine clinical trial for children with acute leukemia. The three organizations share a commitment to address the urgent need for new, more precise and more effective treatments for children with cancer. The new study, called LLS PedAL (Pediatric Acute Leukemia), is a master clinical ...

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LLS Announces Collaboration with the National Cancer Institute and Children’s Oncology Group on a Global Master Clinical Trial for Children with Acute Leukemia

New Study to Test Precision Medicine Treatments to Improve Outcomes for Children with Leukemia

June 17, 2020 (Rye Brook, NY) - The Leukemia & Lymphoma Society (LLS) announced today a collaboration with the National Cancer Institute (NCI) and the Children’s Oncology Group (COG) to launch a global precision medicine clinical trial for children with acute leukemia. The three organizations share a commitment to address the urgent need for new, more precise and more effective trea ...

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LLS Announced a Collaboration with the National Cancer Institute and Children’s Oncology Group on a Global Master Clinical Trial for Children with Acute Leukemia

New Study to Test Precision Medicine Treatments to Improve Outcomes for Children with Leukemia

June 17, 2020 (Rye Brook, NY)  -The Leukemia & Lymphoma Society (LLS) announced today a collaboration with the National Cancer Institute (NCI) and the Children’s Oncology Group (COG) to launch a global precision medicine clinical trial for children with acute leukemia. The three organizations share a commitment to address the urgent need for new, more precise and more effec ...

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Leukemia Patient’s Legacy Helps Drive Innovative Cancer Clinical Trial

Major Donation from The Harry T. Mangurian Jr. Foundation Helps The Leukemia & Lymphoma Society Expand its Assault on Deadly Cancer

Rye Brook, NY (March 21, 2018) - Turning sorrow into action, The Harry T. Mangurian Jr. Foundation, whose namesake died from acute myeloid leukemia (AML), continues to fuel The Leukemia & Lymphoma Society’s (LLS) ambitious attack on this deadly blood cancer.  Specifically, with the Foundation’s support, LLS is leading a paradigm shift ...

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Glossary Results

Clinical trials

Careful studies done by doctors to test new drugs or treatments, or new uses for approved drugs or treatments. The goal of clinical trials for blood cancers is to improve treatment and quality of life and to find cures.

Epigenetic Change

Any change that alters gene activity without changing the DNA sequence. Many types of epigenetic changes have been identified. While epigenetic changes are natural and essential to many of the body's functions, certain epigenetic changes can cause major adverse health effects, including cancer. Drugs that target specific epigenetic changes - for example, the histone deacetylase (HDAC) inhibitor vorinostat (Zolinza® )- are approved to treat some blood cancers and are being studied in clinical trials for treatment of other blood cancers