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Clinical trials

Careful studies done by doctors to test new drugs or treatments, or new uses for approved drugs or treatments. The goal of clinical trials for blood cancers is to improve treatment and quality of life and to find cures.

Epigenetic Change

Any change that alters gene activity without changing the DNA sequence. Many types of epigenetic changes have been identified. While epigenetic changes are natural and essential to many of the body's functions, certain epigenetic changes can cause major adverse health effects, including cancer. Drugs that target specific epigenetic changes - for example, the histone deacetylase (HDAC) inhibitor vorinostat (Zolinza® )- are approved to treat some blood cancers and are being studied in clinical trials for treatment of other blood cancers

Clinical Trials or Standard Treatment? Understanding Options for Blood Cancers

March 18, 2015

Topics Covered The role of clinical trials in blood cancer treatment How clinical trials are designed How to determine the best treatment option for you Talking to your healthcare team about treatment options Speaker John P. Leonard, MD
Associate Dean for Clinical Research
Weill Cornell Medical College
New York, NY

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How a Clinical Trial Works

Clinical trials are conducted worldwide under rigorous guidelines to help doctors find out whether new cancer treatments are safe and effective or better than the standard treatment. Before a trial begins, a new therapy is often developed and tested in a laboratory. It's then thoroughly tested in animals. If this early research (the preclinical testing) shows promise that the therapy may be safe and effective, a carefully planned and monitored clinical trial of the drug or treatment will ...

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Transforming Blood Cancer Care: The Role of Clinical Trials and CAR T-Cell Therapy

Held in conjunction with the Oncology Nursing Society 41st Annual Congress There is no fee for this educational activity.

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Are Clinical Trials Safe?

U.S. clinical trials are designed to give patients the safest, potentially most effective clinical therapies. Clinical trials are conducted once researchers have shown in the laboratory and in animal research that a particular study treatment has a good chance of offering better outcomes for people with a specific disease. Patients enrolled in cancer clinical trials are never treated as “guinea pigs.” In fact, patients are given either The best treatment currently availabl ...

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Clinical Trials and Insurance Issues

Once you've identified a clinical trial you may want to join, you'll need to consider how your care will be paid for. Insurance coverage for clinical trials varies depending on the treatment, the insurance company and the health insurance policy. The study sponsor may cover some of the clinical trial costs. Most studies provide the drug or treatment free of charge. Other costs may or may not be covered by health insurance plans. Speak with the clinical trial sponsor and your insurance pr ...

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Glossary Results

Clinical trials

Careful studies done by doctors to test new drugs or treatments, or new uses for approved drugs or treatments. The goal of clinical trials for blood cancers is to improve treatment and quality of life and to find cures.

Epigenetic Change

Any change that alters gene activity without changing the DNA sequence. Many types of epigenetic changes have been identified. While epigenetic changes are natural and essential to many of the body's functions, certain epigenetic changes can cause major adverse health effects, including cancer. Drugs that target specific epigenetic changes - for example, the histone deacetylase (HDAC) inhibitor vorinostat (Zolinza® )- are approved to treat some blood cancers and are being studied in clinical trials for treatment of other blood cancers