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Clinical trials

Careful studies done by doctors to test new drugs or treatments, or new uses for approved drugs or treatments. The goal of clinical trials for blood cancers is to improve treatment and quality of life and to find cures.

Epigenetic Change

Any change that alters gene activity without changing the DNA sequence. Many types of epigenetic changes have been identified. While epigenetic changes are natural and essential to many of the body's functions, certain epigenetic changes can cause major adverse health effects, including cancer. Drugs that target specific epigenetic changes - for example, the histone deacetylase (HDAC) inhibitor vorinostat (Zolinza® )- are approved to treat some blood cancers and are being studied in clinical trials for treatment of other blood cancers

Cancer Treatment: How to Make Informed Choices about Standard of Care and Clinical Trials

Please join The Leukemia & Lymphoma Society for a patient education program on making cancer treatment decisions.

Speaker: Jeffrey E. Lancet, MD, Chair Department of Malignant Hematology
Organization/Affiliation: Moffitt Cancer Center With a Patient and Healthcare Professional Panel Discussion •    Rami Komrokji, MD – Myelodysplastic Syndrome and Acute Myeloid Leukemia
•    Lubomir Sokol, MD, PhD – Lymphomas
• & ...

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Clinical Trial Support Center (CTSC) Referral Process for Healthcare Providers

LLS Clinical Trial Support Center (CTSC) Nurse Navigators are available, at no cost, to help healthcare professionals and patients find and answer questions about clinical trials. Our Nurse Navigators are specially trained not only in blood cancers and clinical trials, but also patient education and support.  Physicians, their care teams, and their patients and caregivers have direct access to their CTSC Nurse Navigator throughout the trial search and enrollment process, and ...

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MD Anderson Starts LLS-Funded Clinical Trial for Acute Myeloid Leukemia

The Leukemia & Lymphoma Society funds phase I study of new approach to starving cancer

Houston, TX- October 26, 2016 -- The University of Texas MD Anderson Cancer Center’s Institute for Applied Cancer Science (IACS) has initiated the first clinical study of a novel drug designed to starve cancer cells, IACS-10759. The study will enroll patients with acute myeloid leukemia (AML) and is supported by a $3.5 million investment from The Leukemia & Lymphoma Society (LLS) The ...

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Clinical Trials

Clinical Trials: Everything You Need to Know Podcast episode featuring LLS's Clinical Trial Nurse Navigator, Neena Kennedy, BSN, RN, OCN. 
Listen Now Source: nbmtLINK's Marrow Masters Podcast
Taking part in a clinical trial may be the best treatment choice for some blood cancer patients. There are trials for patients at every stage of treatment as well as those in remission. Virtually all of today's standard treatments for cancer are based on previ ...

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Finding a Clinical Trial

If you're interested in the possibility of a clinical trial as a treatment option, talk with your doctor first. He or she can help you find an eligible trial. You can also contact one of The Leukemia & Lymphoma Society's (LLS's) Information Specialists for help in finding an appropriate clinical trial. We can help you identify the information you need about your diagnosis and treatment history to determine eligible trials. We can also help you develop a list of qu ...

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Glossary Results

Clinical trials

Careful studies done by doctors to test new drugs or treatments, or new uses for approved drugs or treatments. The goal of clinical trials for blood cancers is to improve treatment and quality of life and to find cures.

Epigenetic Change

Any change that alters gene activity without changing the DNA sequence. Many types of epigenetic changes have been identified. While epigenetic changes are natural and essential to many of the body's functions, certain epigenetic changes can cause major adverse health effects, including cancer. Drugs that target specific epigenetic changes - for example, the histone deacetylase (HDAC) inhibitor vorinostat (Zolinza® )- are approved to treat some blood cancers and are being studied in clinical trials for treatment of other blood cancers