Vincristine sulfate liposome injection

Details of the Drug

Generic Name:: Vincristine sulfate liposome injection
Pronunciation:: vin-KRIS-teen SUHL-feyt
Drug Type:: Antimitotic
How the Drug is Given:: Intravenously (IV) (fatal if given by other routes)
Names:: Marqibo®; Vincristine sulfate liposome injection

Indications and Usage

Vincristine sulfate liposome injection is FDA approved for the treatment of adult patients with Philadelphia chromosome-negative (Ph-) acute lymphoblastic leukemia (ALL) in second or greater relapse or whose disease has progressed following two or more anti-leukemia therapies.

Side effects needing medical attention

Constipation; bowel obstruction; nausea; fever; fatigue; diarrhea; decreased appetite; insomnia; low blood cell counts; pneumonia; life-threatening low blood pressure; infection; peripheral sensory and motor neuropathy; lack of strength; muscular weakness; respiratory distress; respiratory failure; pain; abdominal pain; hypotension; mental status changes; cardiac arrest.

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