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Therapeutic development of mesothelin antibody-drug conjugate anetumab ravtansine in mesothelin expressing childhood AML

Douglas Hawkins

Douglas Hawkins


The Children's Hospital of Philadelphia

Project Term: December 1, 2017 - November 30, 2021

We propose to evaluate clinical and pre-clinical utility of mesothelin directed antibody-drug conjugate anetumab ravtansine in childhood AML. Clinical development and pre-clinical assessment of this agent’s efficacy will be conducted in parallel to facilitate timely transition of this agent to children with relapsed AML.

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