Haopeng Yang, PhD
The University of Texas MD Anderson Cancer Center
I am an instructor working in the Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center. My research roles involve characterizing key epigenetic regulations in B cell lymphoma, elucidating how they contribute to lymphomagenesis, and exploiting these newly uncovered mechanisms for therapeutic purposes. I am tremendously grateful for the generous support from the Leukemia & Lymphoma Society Career Development Program. Our proposed research is aiming to characterize the epigenetic consequences in follicular lymphoma patients with different combinations of multiple genetic alterations and provide with a novel therapeutic approach by targeting the dominant-negative role of hotspot mutants and reversing the imbalance of epigenetic reprogramming. Support from this LLS fellow award will significantly help us address the relevant biological problems and accelerate the translation to a therapeutic purpose.