|Brand name(s), other common name(s)||Blincyto®|
|Drug type||Monoclonal antibody|
|How the drug is given||Intravenously (IV)|
Indications and Usage
Blinatumomab is FDA approved to treat patients with Philadelphia chromosome-negative relapsed or refractory B-cell precursor acute lymphoblastic leukemia (ALL).
Side effects needing medical attention
Fever, headache, swelling of tissues, fever with a low number of white blood cells, nausea, low potassium, fatigue, constipation, diarrhea and tremor.
Blinatumomab carries a boxed warning alerting patients and health care professionals that some clinical trial participants had problems with low blood pressure and difficulty breathing (cytokine release syndrome) at the start of the first treatment, experienced a short period of difficulty with thinking (encephalopathy) or other side effects in the nervous system.