May 21, 2013 - Living with Slow-Growing Lymphoma
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- Follicular and other slow-growing lymphomas
- Current and emerging treatments, including stem cell transplant, for follicular and other slow-growing lymphomas
- The role of clinical trials in the advancement of treatment
- Patient-provider communications about treatment options, including clinical trials
- Patient-provider communications about side effects management
Stephen M. Ansell, MD, PhD
Professor of Medicine
Division of Hematology
Department of Internal Medicine
Questions Asked by the Slow-Growing Lymphoma Community
- What does grade 3 follicular lymphoma mean and how are follicular lymphomas graded?
- Could you speak a little bit more about maintenance rituximab (Rituxan®) therapy?
- Are six rounds of Ritxuan and bendamustine (Treanda®) necessary or can one get by on fewer rounds if the therapy is working?
- Would Rituxan maintenance be a good idea or would watch and wait be a better treatment option after a second relapse with follicular lymphoma?
- Please talk about the role and outcomes of radioimmunotherapy as a treatment option for slow-growing lymphomas.
- What would be the best sort of chemical combination to use after relapsing with small B-cell lymphocytic lymphoma?
- Does age at diagnosis change the prognosis or the course of the disease?
- Is it possible to become resistant to Rituxan if a patient hasn't been treated with it for a while?
- If a patient is resistant to Rituxan, is the patient likely to be refractory to ofatumumab (Arzerra®) as well as the other CD20 antibodies?
- Is follicular non-Hodgkin lymphoma inherited?
- Can Rituxan increase LDH levels months after chemo treatment?
- What is considered a relapse after Rituxan maintenance for two years?
- Can one have an allogeneic transplant if their bone marrow is involved with the lymphoma?
- If a patient has a diagnosis of subcutaneous panniculitis-like T-cell lymphoma and is treated with cyclosporine with a combination of prednisone, was weaned off the cyclosporine but still on maintenance prednisone, would the patient be able to go back on the cyclosporine if it worked before?
- Besides the BTK inhibitor, are there any other new tyrosine kinase inhibitors that show promise?
- How do treatments affect the bone marrow?
- When will some of these novel treatments and drugs in clinical trials be available more widely?
- Do you have to be near a clinical trial site to participate?
- What are CDK inhibitors?
- Should I be concerned about radiation from the monitoring scans?
- Are severe leg cramps a side effect of cancer treatment?
- Can you go back a stage? For instance, if you're in stage III, can you go back to stage II if you have a lymph node removed?
- Can you talk about ibrutinib and what would it mean for Waldenstrom's macroglobulinemia?
- Would Medicare pay for ibrutinib if it is approved or only for the specific lymphomas it's been approved for?
- Is it possible to be over-treated?
- What percentages of people are in remission from follicular lymphoma?
- If lymphoma is in the bone marrow, will it ever spread to other areas in the body?
- Is Idiopathic thrombocytopenic purpura (ITP) related to low grade lymphoma or is it something totally different?