Epigenetics in Hematologic Malignancies: Pathogenesis and Therapy Note: The free Adobe Acrobat Reader® is required to view and print Adobe PDF files, and the free Windows Media Player or RealPlayer is required to listen to the MP3 audio files. Internet Release Date: February 22, 2012 Credit Available Until: February 22, 2013 Target Audience: Hematologists, oncologists, nurses, social workers and other healthcare professionals Access: Virtual Lecture Activity Purpose This free activity, entitled "Epigenetics in Hematologic Malignancies: Pathogenesis and Therapy," consists of a program overview, 5 presentations with Q&A, a Learning Assessment, and an Evaluation form. The content of this virtual lecture is derived from a symposium presented on December 9, 2011, in San Diego, California. It is designed for hematologists, oncologists, nurses, social workers and other healthcare professionals who wish to enhance their knowledge of advances in epigenetic research and implications in treating patients with hematologic malignancies. Educational Objectives After completing this activity, the participant should be better able to: Describe how epigenetic changes affect gene expression and contribute to malignant changes in blood cancer cells Discuss new strategies for the development of blood cancer therapies which inhibit factors that produce epigenetic changes in blood cancer cells Discuss the therapeutic potential of targeting epigenetic changes as they relate specifically to leukemia, lymphoma and myeloma Utilize the information presented from current trials and best practices focusing on epigenetic therapies to better manage their patients with hematologic malignancies Faculty Stephen B. Baylin, MD Deputy Director, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Research Professor of Oncology Johns Hopkins University Baltimore, MD James E. Bradner, MD Attending Physician, Hematology-Oncology Assistant Professor of Medicine Dana-Farber Cancer Institute Harvard Medical School Boston, MA Jean-Pierre Issa, MD Professor of Medicine Director, Fels Institute for Cancer Research & Molecular Biology Temple University School of Medicine Philadelphia, PA Ross L. Levine, MD Associate Member, Human Oncology & Pathogenesis Program Associate Attending Physician, Leukemia Service, Department of Medicine Geoffrey Beene Junior Faculty Chair Memorial Sloan-Kettering Cancer Center Assistant Professor of Medicine and Ce./Developmental Biology Weill Cornell Medical College New York, NY Jonathan D. Licht, MD Johanna Dobe Professor and Chief Division of Hematology/Oncology Associate Director, Clinical Sciences Robert H. Lurie Comprehensive Cancer Center Northwestern University Chicago, IL Sponsors and Supporters This activity was jointly sponsored by RMEI, LLC and Postgraduate Institute for Medicine in collaboration with The Leukemia & Lymphoma Society and was supported by educational grants from Millennium: The Takeda Oncology Company, Celgene Corporation and Allos Therapeutics, Inc.
Epigenetics in Hematologic Malignancies: Pathogenesis and Therapy