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Glossary Results

Relapsed CLL

CLL that responded to treatment but then returns.

Refractory CLL

CLL that has not responded to initial treatment. Refractory disease may be disease that is getting worse or staying the same (stable disease).

CD38

An antigen on CLL cells and other cells. The expression of CD38 may be a marker to assist in predicting CLL progression.

Richter transformation

In a small number of patients, there is a progression in their disease. In these patients, CLL takes on the characteristics of an aggressive lymphoma. This change is not a second cancer, but a transformation of the CLL cells.

Small lymphocytic lymphoma (SLL)

A disease with symptoms and treatment that are much like CLL. SLL starts in a lymphocyte in a lymph node. CLL starts in a lymphocyte in the marrow.

Immunoglobulin Heavy Chain Variable Region (IgHv) Gene Status

A marker that can distinguish between CLL subtypes (unmutated IgHv and mutated IgHv). People with CLL with unmutated IgHv gene status may have a more progressive form of the disease.

Zap-70

An abbreviation for the cell protein “zeta-associated protein 70.” A high level of ZAP-70 expression on the cells of patients with B-cell CLL is one of several factors that may predict more progressive disease. Outside of a research laboratory this test is generally not very reliable and should not be used.

CLL Staging

Doctors use staging to help them predict chronic lymphocytic leukemia's (CLL's) progression and develop an appropriate treatment plan. Doctors use one of two staging systems: the Rai staging system or the Binet staging system. Both systems use physical examination and laboratory parameters to assess the extent of disease and to classify patients into three major prognostic groups.  Staging systems for CLL take into account: Abnormal increase in number of lymphocytes (lymp ...

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LIVING WELL WITH CLL: DIAGNOSIS, TREATMENT AND SUPPORT

Join us for an informative new program that takes you through all phases of the CLL journey: from diagnosis through treatment and into survivorship.

Location
The Lodge at Des Peres
1050 Des Peres Road
Des Peres, MO 63131  

Speakers
Nancy Bartlett, MD, Professor, Siteman Cancer Center, Washington University School of Medicine
Ashleigh Wesselschmidt, ANP, iteman Cancer Center, Washington University School of Medicine
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Living Well with CLL: diagnosis, treatment and support

Join us for an informative new program that takes you through all phases of the CLL journey: from diagnosis through treatment and into survivorship.

Location
Maggiano’s Restaurant
3106 West End Avenue
Nashville, TN 37203 
Self-park and Valet are both available

Registration:  5:30pm 
Dinner & Program:  6:00pm

Speakers
Ian Flinn, MD, Tennessee Oncology
Kelly Owen, LMSW, Vanderbilt U ...

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Living Well with CLL: diagnosis, treatment and support

Join us for an informative new program that takes you through all phases of the CLL journey: from diagnosis through treatment and into survivorship

Location
The Mandalay Banquet & Event Center
2700 E. River Road
Moraine, OH 45439   Speakers
Brandon Cutler, DO, Kettering Physician Network
Lynn M. Foubert, MSW, LISW-S, ACHP-SW, Premier Health Time
Registration and Dinner:  6:00pm
Program:  6:30pm    & ...

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Living Well with CLL: diagnosis, treatment and support

Join us for an informative new program that takes you through all phases of the CLL journey: from diagnosis through treatment and into survivorship.

Location
Hotel Indigo Athens
500 College Avenue
Athens, GA 30601
(Parking is available at 165 Dougherty Street after 5 pm)

Speaker
Gustavo Westin, MD, MPH
University Cancer & Blood Center

Program Description
This program is designed to provide attendees wi ...

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Glossary Results

Relapsed CLL

CLL that responded to treatment but then returns.

Refractory CLL

CLL that has not responded to initial treatment. Refractory disease may be disease that is getting worse or staying the same (stable disease).

CD38

An antigen on CLL cells and other cells. The expression of CD38 may be a marker to assist in predicting CLL progression.

Richter transformation

In a small number of patients, there is a progression in their disease. In these patients, CLL takes on the characteristics of an aggressive lymphoma. This change is not a second cancer, but a transformation of the CLL cells.

Small lymphocytic lymphoma (SLL)

A disease with symptoms and treatment that are much like CLL. SLL starts in a lymphocyte in a lymph node. CLL starts in a lymphocyte in the marrow.

Immunoglobulin Heavy Chain Variable Region (IgHv) Gene Status

A marker that can distinguish between CLL subtypes (unmutated IgHv and mutated IgHv). People with CLL with unmutated IgHv gene status may have a more progressive form of the disease.

Zap-70

An abbreviation for the cell protein “zeta-associated protein 70.” A high level of ZAP-70 expression on the cells of patients with B-cell CLL is one of several factors that may predict more progressive disease. Outside of a research laboratory this test is generally not very reliable and should not be used.