The prognosis (the likely outcome of the disease) varies widely in patients with MF. Each patient's prognostic risk factors are evaluated differently. A very large proportion of symptom-free patients remain stable for years without needing treatment.
The average survival time after an MF diagnosis is about five years. People younger than 55 and with good prognostic factors have an average survival of 11 years. Better outcomes are associated with the absence of abnormal chromosomes, hemoglobin levels above 10 grams per deciliter, symptoms, elevated white cell count and a younger age.