Disease Information & Support


The Word:


Generic name Romidepsin
Pronunciation roh-mi-DEP-sin
Brand name(s), other common name(s) Istodax®
Drug type  Histone deacetylase inhibitor
How the drug is given Intravenously (IV)

Romidepsin is FDA approved for the treatment of patients with cutaneous T-cell lymphoma (CTCL) who have received at least one prior systemic therapy and treatment of patients with peripheral T-cell lymphoma (PTCL) who have received at least one prior therapy.

Side effects needing medical attention: Excessive nausea or vomiting; abnormal heartbeat; chest pain or shortness of breath; unusual bleeding; fever; cough; flu-like symptoms; burning on urination; muscle aches; worsening of skin problems; persistent diarrhea; loss of appetite; tiredness; infections; abdominal pain; low levels of magnesium, calcium, potassium or sodium in blood; low blood cell counts; changes in taste; constipation; hypotension; itchy skin; electrocardiogram T-wave changes; hyperglycemia.


For information on how to manage the costs of drug therapy, please see Financial Matters and Prescription Drug Coverage, or to speak with an Information Specialist, call (800) 955-4572.

last updated on Wednesday, February 19, 2014