Disease Information & Support


The Word:


Generic name Mechlorethamine
Pronunciation me-klor-ETH-a-meen
Brand name(s), other common name(s) Mustargen®, nitrogen mustard
Drug type  DNA-damaging agent
How the drug is given Intravenously (IV)

Mechlorethamine is FDA approved to treat people who have Hodgkin lymphoma, chronic myeloid leukemia, chronic lymphocytic leukemia, polycythemia vera and mycosis fungoides.

Side effects needing medical attention: If mechlorethamine accidentally seeps out of the vein, it may damage some tissues and cause scarring. Your healthcare provider should be notified right away if you notice redness, pain or swelling at the IV site; wheezing; fever; chills; sore throat; missed menstrual periods; painful rash; unusual bleeding or bruising; dizziness; side and stomach pain; loss of hearing; ringing in ears; swelling of feet or lower legs; black, tarry stools; itching; numbness, tingling or burning of fingers, toes or face; shortness of breath; yellowing of eyes and skin 

Side effects needing medical attention after stopping this medication: Fever; chills; sore throat; unusual bleeding or bruising.


For information on how to manage the costs of drug therapy, please see Financial Matters and Prescription Drug Coverage, or to speak with an Information Specialist, call (800) 955-4572.

last updated on Monday, October 15, 2012