Disease Information & Support


The Word:


Generic name Leucovorin
Pronunciation loo-koh-VOR-in
Brand name(s), other common name(s) folinic acid
Drug type  Vitamin
How the drug is given Intravenously (IV) or by intramuscular (IM) injection

Leucovorin is an FDA-approved drug similar to the vitamin folic acid. It protects healthy cells from the effects of methotrexate while allowing methotrexate to enter and kill cancer cells.

Levoleucovorin (Fusilev®) is a form of leucovorin that is given intravenously (IV).

Side effects needing medical attention: Allergic-like reactions; fatigue; weakness; nausea; vomiting; diarrhea; constipation; loss of appetite.


For information on how to manage the costs of drug therapy, please see Financial Matters and Prescription Drug Coverage, or to speak with an Information Specialist, call (800) 955-4572.

last updated on Thursday, October 18, 2012