Disease Information & Support


The Word:


Generic name Dasatinib
Pronunciation da-SAT-i-nib
Brand name(s), other common name(s) Sprycel®
Drug type  Tyrosine kinase inhibitor
How the drug is given By mouth

Dasatinib is FDA approved to treat all phases of chronic myeloid leukemia or a type of acute lymphoblastic leukemia called Philadelphia chromosome positive or Ph+ ALL in adults who are no longer benefiting from treatment with the current available therapies for these diseases, including Gleevec® (imatinib mesylate), or who experience severe side effects from Gleevec®.

Special considerations: Tell your doctor if you have any other medical conditions, especially if you have a liver or heart problem or are lactose intolerant.

Side effects needing medical attention: Fever; bleeding or easy bruising; swelling; weight gain; increasing shortness of breath.

Dasatinib may increase the risk of a rare but serious condition in which there is abnormally high blood pressure in the arteries of the lungs (pulmonary arterial hypertension [PAH]). Symptoms of PAH may include shortness of breath, fatigue, and swelling of the body (such as the ankles and legs).


For information on how to manage the costs of drug therapy, please see Financial Matters and Prescription Drug Coverage, or to speak with an Information Specialist, call (800) 955-4572.

last updated on Monday, October 15, 2012