Disease Information & Support


The Word:


Generic name Cyclophosphamide
Pronunciation sy-kloh-FOS-fa-mide
Brand name(s), other common name(s) Cytoxan®
Drug type  DNA-damaging agent
How the drug is given By mouth or intravenously (IV)

Cyclophosphamide is FDA approved to treat several types of cancer, including people who have Hodgkin lymphoma, non-Hodgkin lymphoma, acute and chronic lymphocytic leukemia, acute and chronic myeloid leukemia, myeloma, and mycosis fungoides. Cyclophosphamide is usually used in combination with other drugs.

Cyclophosphamide may cause a temporary loss of hair in some people. After treatment has ended, normal hair growth should return, although the new hair may be a slightly different color or texture.

Side effects needing medical attention: If the patient is receiving this medicine by injection: redness, swelling or pain at the place of injection. All recipients: blood in urine; dizziness, confusion or agitation; fever; chills; sore throat; missed menstrual periods; tiredness; cough; side or stomach pain; joint pain; shortness of breath; swelling of feet or lower legs; unusual bleeding or bruising; unusually fast heartbeat; black, tarry stools; sores in mouth and on lips; painful, difficult or unusually frequent urination; excessive thirst; yellow eyes and skin; pinhead-sized red spots on skin or rash; darkening of skin and fingernails; loss of hair; nausea or vomiting (if severe); diarrhea; redness of face; headache; sweating; itching; swollen lips.

Side effects needing medical attention after stopping this medication: Blood in urine.


For information on how to manage the costs of drug therapy, please see Financial Matters and Prescription Drug Coverage, or to speak with an Information Specialist, call (800) 955-4572.

last updated on Monday, October 15, 2012